Afraxis is discovering and developing drugs to treat diseases through the modulation of p21-activated kinase (PAK). Afraxis’ initial indication of interest is Fragile X syndrome with future expansion into other CNS diseases, including schizophrenia and autism spectrum disorders. By inhibiting PAK, a protein that regulates the development and maturation of synaptic connections that are defective in mental retardation syndromes and other CNS diseases, Afraxis will target CNS disease modification rather than just treat symptoms. PAK is also implicated in a number of different oncological settings and Afraxis is exploring the potential of PAK inhibitors for the treatment of cancers such as neurofibromatosis, breast cancer and lung cancer.
Backupify is the leading backup provider for cloud application data, offering an all-in-one archiving, search and restore solution for the most popular online services including Google Apps, Salesforce, Facebook, Twitter and more. Backupify ensures that companies can access and control the data they entrust to these systems and prevents data loss from external threats, user error or service failure. Backupify was founded in 2008 and is based in Cambridge, Massachusetts.
Cloudant provides the world’s first globally distributed database-as-a-service (DBaaS) for loading, storing, analyzing, and distributing operational application data for developers of large and/or fast-growing Web and mobile applications. Cloudant’s DBaaS is a managed service that helps developers eliminate the delays, costs, and distractions inherent in working with databases and their administrators, while providing unmatched scalability, availability, and performance. This capability accelerates time-to-market and time-to-innovation because it frees developers from the mechanics of data management so they can focus exclusively on creating great applications. For more information, visitwww.cloudant.com.
Cloudkick provides award-winning cloud server monitoring and management tools, built from the ground up to support modern APIs and the elastic nature of the cloud. From performance monitoring and fault detection to trend visualization and graphing, their tools work across your entire cloud computing infrastructure, no matter what cloud provider you choose.
Cloudkick was acquired by Rackspace.
Kaltura provides the world’s first Open Source Online Video Platform, transforming the way people work, learn and entertain, using video. Kaltura’s platform engages hundreds of millions of viewers, offers next generation learning for millions of students and teachers, and improves productivity and interaction among millions of employees across the globe. Kaltura’s features and products enable organizations to easily deploy video in any website or any web platform.
Otonomy is a clinical stage biopharmaceutical company developing novel drug therapies for disorders of the inner and middle ear. This field represents a large opportunity as there are no approved drug treatments for the nearly 30 million Americans facing debilitating hearing and balance disorders such as Ménière’s disease, sudden sensorineural hearing loss, noise-induced hearing loss, age-related hearing impairment, and tinnitus. Additionally, new therapies are required for otitis media since resistance to oral antibiotics is increasing and short-acting locally administered drugs present significant compliance challenges. Otonomy is working in partnership with leading experts in the field of otology to bring new drug therapies to patients suffering with these conditions.
Simulmedia is a media/marketing company dedicated to improving the effectiveness of program promotion on television. The Company is pioneering the use of sophisticated data analysis and predictive technology to help television companies deliver the right on-air promotions to the right viewers at the right time and build the world’s first full-scaled digital ad targeting platform for linear television. Simulmedia’s unwired audience network reaches all 116 million U.S. TV homes in partnership with seven of the eight largest system operators and more than 30 television networks.
Sova Pharmaceuticals, Inc. is a discovery stage company seeking to make therapeutics to treat central sleep apnea.
Standing Cloud, Inc. is a leading provider of cloud application management services. The Company provides a seamless application layer for cloud service providers, and a cloud management platform for independent software vendors. The service makes application deployment and management fast, simple and hassle-free for end customers.
TwinStrata is an innovator in data storage, data protection and disaster recovery solutions using cloud storage. CloudArray® iSCSI storage gateway makes cloud storage as fast, safe and easy to use as local storage. Both CloudArray virtual and physical appliances configure in minutes and integrate public cloud, private cloud and existing storage devices into flexible “Cloud SANs” that provide unlimited storage capacity, without the capital and maintenance expenses of traditional storage. TwinStrata offers its products through a network of IT service providers, systems integrators, OEMs and direct-to-end users.
Zacharon Pharmaceuticals, Inc. is leveraging unique glycobiology expertise to develop an entirely new class of human therapeutics targeting glycans, the carbohydrate portions of glycoproteins, proteoglycans, and glycolipids. Glycans provide attractive targets for a variety of human diseases including lysosomal storage diseases, oncology, inflammation, and others. To unlock this potential, Zacharon created an innovative glycan-targeted drug development platform, a technology breakthrough enabling a new class of human therapeutics addressing substantial unmet needs.
Zynga is the # 1 social gaming company on the web. Zynga was founded on the notion that casual games are far more fun, interesting and compelling when you can play with your friends. Zynga’s games run inside social networks and mobile platforms and take advantage of the pre-existing social graphs. Zynga was founded by Mark Pincus and is based in San Francisco.
